Monday, 8 October 2012

Polysaccharide-Iron Elixir


Pronunciation: PAHL-ee-SAA-kah-ride-EYE-run
Generic Name: Polysaccharide-Iron
Brand Name: Niferex

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children younger than 6 years of age. Keep this and all medicines out of reach of children. In case of accidental ingestion, call the poison control center or a doctor immediately.





Polysaccharide-Iron Elixir is used for:

Treating and preventing low levels of iron in the blood caused by certain types of anemia. It may also be used for other conditions as determined by your doctor.


Polysaccharide-Iron Elixir is an essential body mineral. It works by replacing iron in your body if your body does not produce enough on its own.


Do NOT use Polysaccharide-Iron Elixir if:


  • you are allergic to any ingredient in Polysaccharide-Iron Elixir

  • you have high levels of iron in your blood

Contact your doctor or health care provider right away if any of these apply to you.



Before using Polysaccharide-Iron Elixir:


Some medical conditions may interact with Polysaccharide-Iron Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have inflammation of the intestines, Crohn disease, digestive problems, ulcers, anemia, or a blood disease (eg, porphyria, thalassemia)

  • if you have had multiple blood transfusions

  • if you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Polysaccharide-Iron Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Doxycycline, mycophenolate, penicillamine, or thyroid hormones (eg, levothyroxine) because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Polysaccharide-Iron Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Polysaccharide-Iron Elixir:


Use Polysaccharide-Iron Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Polysaccharide-Iron Elixir may be taken with food if it upsets your stomach.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • Do not take Polysaccharide-Iron Elixir within 1 hour before or 2 hours after antacids, eggs, whole grain breads, cereal, milk, milk products, coffee, or tea.

  • Take Polysaccharide-Iron Elixir with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Polysaccharide-Iron Elixir.

  • If you are also taking a bisphosphonate (eg, alendronate), a cephalosporin (eg, cephalexin), methyldopa, penicillamine, a quinolone (eg, ciprofloxacin), or a tetracycline (eg, minocycline) along with Polysaccharide-Iron Elixir, you may need to space the doses several hours apart. Ask your doctor or pharmacist how much time is needed between doses of Polysaccharide-Iron Elixir and your other medicines.

  • If you miss a dose of Polysaccharide-Iron Elixir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Polysaccharide-Iron Elixir.



Important safety information:


  • Do not take large doses of vitamins (megadoses or megavitamin therapy) while taking Polysaccharide-Iron Elixir unless directed to by your doctor.

  • Do not exceed the recommended dose or take Polysaccharide-Iron Elixir for longer than 6 months without checking with your doctor.

  • Polysaccharide-Iron Elixir may cause your stools to darken. This is normal and not a cause for concern.

  • Polysaccharide-Iron Elixir contains iron. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children younger than 6 years of age. In case of accidental overdose, call a doctor or poison control center immediately.

  • Polysaccharide-Iron Elixir may interfere with certain lab tests, such as tests used to check for blood in the stool. Make sure your doctor and laboratory personnel know you are using Polysaccharide-Iron Elixir.

  • LAB TESTS, including blood tests and iron levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Polysaccharide-Iron Elixir with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Polysaccharide-Iron Elixir, discuss with your doctor the benefits and risks of using Polysaccharide-Iron Elixir during pregnancy. Polysaccharide-Iron Elixir is excreted in breast milk. If you are or will be breast-feeding while you are using Polysaccharide-Iron Elixir, check with your doctor or pharmacist to discuss the risks to your baby.


Possible side effects of Polysaccharide-Iron Elixir:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; darkened or green stools; diarrhea; nausea; stomach upset.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting, especially with continuing sharp stomach pain.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Polysaccharide-Iron side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; loss of consciousness; seizures; severe nausea or diarrhea; stomach pain; tarry stools; unusual tiredness or drowsiness; unusually pale skin; vomiting; vomiting blood; weak, fast heartbeat.


Proper storage of Polysaccharide-Iron Elixir:

Store Polysaccharide-Iron Elixir at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Polysaccharide-Iron Elixir out of the reach of children and away from pets.


General information:


  • If you have any questions about Polysaccharide-Iron Elixir, please talk with your doctor, pharmacist, or other health care provider.

  • Polysaccharide-Iron Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Polysaccharide-Iron Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Polysaccharide-Iron resources


  • Polysaccharide-Iron Side Effects (in more detail)
  • Polysaccharide-Iron Dosage
  • Polysaccharide-Iron Use in Pregnancy & Breastfeeding
  • Drug Images
  • Polysaccharide-Iron Drug Interactions
  • Polysaccharide-Iron Support Group
  • 3 Reviews for Polysaccharide-Iron - Add your own review/rating


Compare Polysaccharide-Iron with other medications


  • Iron Deficiency Anemia

Sunday, 7 October 2012

Thymoglobulin


Pronunciation: AN-tye THYE-moe-site GLOB-yoo-lin
Generic Name: Anti-Thymocyte Globulin (Rabbit)
Brand Name: Thymoglobulin

Thymoglobulin should only be given by a doctor in a medical setting under the supervision of a doctor who is experienced in management of organ transplant patients.





Thymoglobulin is used for:

Treating acute kidney transplant rejection with other medicines used to suppress the immune system. It may also be used for other conditions as determined by your doctor.


Thymoglobulin is an immune globulin. It works by suppressing the body's immune response, but the way it does this is not fully understood.


Do NOT use Thymoglobulin if:


  • you are allergic to any ingredient in Thymoglobulin

  • you are allergic to rabbit products

  • you have an acute viral illness

Contact your doctor or health care provider right away if any of these apply to you.



Before using Thymoglobulin:


Some medical conditions may interact with Thymoglobulin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have heart failure, shortness of breath, or swelling in the legs

  • if you have low blood platelets or a low white blood cell count

  • if you have high blood sodium or potassium, or kidney or liver problems

Some MEDICINES MAY INTERACT with Thymoglobulin. However, no specific interactions with Thymoglobulin are known at this time.


This may not be a complete list of all interactions that may occur. Ask your health care provider if Thymoglobulin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Thymoglobulin:


Use Thymoglobulin as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Thymoglobulin is only administered as an injection by health care providers in a medical setting.

  • If Thymoglobulin contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.

  • You may be given other medicines (eg, acetaminophen, corticosteroids, an antihistamine) to decrease the side effects of Thymoglobulin.

  • If you miss a dose of Thymoglobulin, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Thymoglobulin.



Important safety information:


  • Thymoglobulin may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Thymoglobulin. Using Thymoglobulin alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.

  • Thymoglobulin may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.

  • Thymoglobulin may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first. Notify your doctor of any signs of infection including fever, sore throat, rashes, or chills.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Thymoglobulin.

  • Thymoglobulin can affect the results of certain lab tests. Make sure lab personnel and your doctors know you use Thymoglobulin.

  • Check with your doctor before having vaccinations while you are using Thymoglobulin.

  • Carry an identification card at all times that says you taking this medication.

  • LAB TESTS, including blood tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Thymoglobulin with caution in CHILDREN. Safety and effectiveness have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Thymoglobulin during pregnancy. It is unknown if Thymoglobulin is excreted in breast milk. If you are or will be breast-feeding while you are using Thymoglobulin, check with your doctor or pharmacist to discuss the risks to your baby.


Possible side effects of Thymoglobulin:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Chills; diarrhea; dizziness; fever; general body discomfort; headache; nausea; swelling of the hands and feet; urinary tract infection; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; dizziness; easy bleeding or bruising; fast or irregular heartbeat; fever; infection; joint or muscle pain; persistent sore throat; stomach pain; unusual fatigue.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Thymoglobulin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Thymoglobulin:

Thymoglobulin is usually handled and stored by a health care provider. If you are using Thymoglobulin at home, store Thymoglobulin as directed by your pharmacist or health care provider. Keep Thymoglobulin out of the reach of children and away from pets.


General information:


  • If you have any questions about Thymoglobulin, please talk with your doctor, pharmacist, or other health care provider.

  • Thymoglobulin is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Thymoglobulin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Thymoglobulin resources


  • Thymoglobulin Side Effects (in more detail)
  • Thymoglobulin Use in Pregnancy & Breastfeeding
  • Thymoglobulin Drug Interactions
  • Thymoglobulin Support Group
  • 0 Reviews for Thymoglobulin - Add your own review/rating


  • Thymoglobulin Prescribing Information (FDA)

  • Thymoglobulin rabbit Concise Consumer Information (Cerner Multum)

  • Thymoglobulin Monograph (AHFS DI)

  • Thymoglobulin Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Thymoglobulin with other medications


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Thursday, 4 October 2012

Gyne-Lotrimin Inserts


Pronunciation: kloe-TRIM-a-zole
Generic Name: Clotrimazole
Brand Name: Gyne-Lotrimin and Mycelex-7


Gyne-Lotrimin Inserts are used for:

Treating vaginal yeast infections.


Gyne-Lotrimin Inserts are an antifungal agent. It works by weakening the cell membrane of the fungus, resulting in the death of the fungus.


Do NOT use Gyne-Lotrimin Inserts if:


  • you are allergic to any ingredient in Gyne-Lotrimin Inserts

  • you have never had a vaginal yeast infection diagnosed by a doctor

  • you have itching caused by a condition other than a yeast infection

  • you have stomach, shoulder, or lower back pain; fever; chills; nausea; foul-smelling vaginal discharge; or vomiting

Contact your doctor or health care provider right away if any of these apply to you.



Before using Gyne-Lotrimin Inserts:


Some medical conditions may interact with Gyne-Lotrimin Inserts. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have the blood disease porphyria or a history of liver disease or diabetes, or you have been exposed to HIV

  • if this is the first time you have had vaginal itching and discomfort

  • if you have vaginal yeast infections often (eg, your symptoms return within 2 months) or your symptoms do not clear up with treatment

  • if you are taking antibiotics

Some MEDICINES MAY INTERACT with Gyne-Lotrimin Inserts. However, no specific interactions with Gyne-Lotrimin Inserts are known at this time.


Ask your health care provider if Gyne-Lotrimin Inserts may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Gyne-Lotrimin Inserts:


Use Gyne-Lotrimin Inserts as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Gyne-Lotrimin Inserts. Talk to your pharmacist if you have questions about this information.

  • Gyne-Lotrimin Inserts are for vaginal use only. Do not use it rectally or take by mouth.

  • Using the applicator provided, insert 1 suppository high into the vagina at bedtime for 7 days.

  • Some forms of this product come with 7 disposable applicators. If this product contains disposable applicators, throw away each applicator after use.

  • Some forms of this product come with one applicator to be used for all 7 days of treatment. If this product contains only one applicator, do not throw it away after use. Separate the pieces of the applicator and wash with warm, soapy water immediately after use. Rinse thoroughly. Make sure the applicator is completely dry before the next use.

  • Wash your hands immediately after using Gyne-Lotrimin Inserts.

  • To clear up your infection completely, use Gyne-Lotrimin Inserts for the full course of treatment. Keep using it even if you feel better in a few days.

  • If you miss a dose of Gyne-Lotrimin Inserts, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Gyne-Lotrimin Inserts.



Important safety information:


  • Gyne-Lotrimin Inserts are for vaginal use only. Avoid contact with the eyes, nose, or mouth. If you get Gyne-Lotrimin Inserts in your eyes, flush with a generous amount of cool water.

  • Be sure to use Gyne-Lotrimin Inserts for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • If your symptoms do not improve within 3 days, if they last more than 7 days, or if they get worse, check with your doctor.

  • Do not use Gyne-Lotrimin Inserts for itching caused by other conditions.

  • Dry the outside vaginal area completely after showering, bathing, or swimming. Do not go swimming for at least 9 to 12 hours after applying Gyne-Lotrimin Inserts. Change out of wet bathing suits or damp workout clothes as soon as possible.

  • Continue using Gyne-Lotrimin Inserts even during your menstrual period. Do not use tampons while you are using Gyne-Lotrimin Inserts or until all of your symptoms go away. Use unscented pads or pantiliners.

  • Do not have vaginal sexual intercourse while you are using Gyne-Lotrimin Inserts.

  • Gyne-Lotrimin Inserts may decrease the effectiveness of condoms and diaphragms, increasing the chance of pregnancy or risk of sexually transmitted disease.

  • Do not use tampons, douches, spermicides, or other vaginal products while using Gyne-Lotrimin Inserts.

  • If you use topical products too often, your condition may become worse.

  • Gyne-Lotrimin Inserts should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Gyne-Lotrimin Inserts while you are pregnant. It is not known if Gyne-Lotrimin Inserts are found in breast milk. If you are or will be breast-feeding while you use Gyne-Lotrimin Inserts, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Gyne-Lotrimin Inserts:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Mild vaginal burning, irritation, or itching.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever or chills; foul-smelling vaginal discharge; nausea; severe or prolonged vaginal burning, irritation, or itching; stomach pain; swelling; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Gyne-Lotrimin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Gyne-Lotrimin Inserts:

Store Gyne-Lotrimin Inserts at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Avoid temperatures above 86 degrees F (30 degrees C). Avoid freezing. Do not store in the bathroom. Do not use if the wrapper on the applicator or suppository is torn or damaged. Keep Gyne-Lotrimin Inserts out of the reach of children and away from pets.


General information:


  • If you have any questions about Gyne-Lotrimin Inserts, please talk with your doctor, pharmacist, or other health care provider.

  • Gyne-Lotrimin Inserts are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Gyne-Lotrimin Inserts. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Gyne-Lotrimin resources


  • Gyne-Lotrimin Side Effects (in more detail)
  • Gyne-Lotrimin Use in Pregnancy & Breastfeeding
  • Gyne-Lotrimin Support Group
  • 0 Reviews for Gyne-Lotrimin - Add your own review/rating


Compare Gyne-Lotrimin with other medications


  • Vaginal Yeast Infection